The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2021
Filed:
Oct. 17, 2019
Senti Biosciences, Inc., South San Francisco, CA (US);
Timothy Kuan-Ta Lu, Cambridge, MA (US);
Russell Morrison Gordley, San Francisco, CA (US);
Jack Tzu-Chiao Lin, Redwood City, CA (US);
Brian Scott Garrison, San Jose, CA (US);
Philip Janmin Lee, Alameda, CA (US);
Alba Gonzalez-Junca, San Francisco, CA (US);
Don-Hong Wang, South San Francisco, CA (US);
Daniel Frimannsson, Alameda, CA (US);
SENTI BIOSCIENCES, INC., South San Francisco, CA (US);
Abstract
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer. Some aspects provide cells engineered to produce multiple effector molecules, each of which modulates a different immunosuppressive mechanisms of a tumor, as well as methods of using the cells to treat cancer, such as ovarian, breast, or colon cancer.