The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2021

Filed:

May. 17, 2017
Applicants:

Piqur Therapeutics Ag, Basel, CH;

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Doriano Fabbro, Arlesheim, CH;

Paul Hebeisen, Basel, CH;

Petra Hillmann-Wuellner, Oberengstringen, CH;

Anton Stuetz, Altmuenster, CH;

John T. Seykora, Broomall, PA (US);

Florent Beaufils, Bartenheim, FR;

Assignee:

TORQUR, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61P 17/02 (2006.01); A61K 31/5386 (2006.01); A61K 31/541 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 31/541 (2013.01); A61P 17/02 (2018.01);
Abstract

The present invention is relates to a compound of formula (I), wherein wherein the arrow denotes the bond in formula (I); andwherein Rand Rare independently of each other H, C-Calkyl optionally substituted with one or two OH, C-Cfluoroalkyl, C-Calkoxy, C-CalkoxyC-Calkyl, CN, or C(O)O—C-Calkyl; or Rand Rform together a bivalent residue —RR— selected from C-Calkylene optionally substituted with 1 to 4 F, —CH—O—CH—, —CH—NH—CH—, or any of the structures wherein the arrows denote the bonds in formula (II); or


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