Biopatch, bioheater, biosensor and bioelectronic patch device

Abstract

A biopatch, a bioheater, a biosensor and a bioelectronic patch device are provided. The biopatch comprises a polymer film comprising a biopolymer and a drug loaded in the polymer film. The biopolymer may comprise one or more than one of a bioabsorbable polymer, a biodegradable polymer and a biocompatible polymer. The biopolymer may comprise oxidized starch. The drug may comprise a first drug chemically combined with the oxidized starch and a second drug physically combined with the oxidized starch. The bioheater comprises a heater comprising biometal. The biometal may comprise Mg or Fe. The heater can be controlled wirelessly by an alternating magnetic field. A biosensor according to one embodiment of the present inventive concept comprises an inductor and a capacitor connected to the inductor, wherein the capacitor comprises a first electrode, a second electrode facing the first electrode and a dielectric disposed between the first electrode and the second electrode, each of the inductor, the first electrode and the second electrode comprises biometal, and the dielectric comprises a biopolymer having a glass transition temperature in a range of 36˜42° C. A biosensor according to another embodiment of the present inventive concept comprises an inductor and a capacitor connected to the inductor, wherein the capacitor comprises a first electrode, a second electrode facing the first electrode and a dielectric disposed between the first electrode and the second electrode, a change in a dielectric constant of the dielectric is transmitted to an external device through a resonance frequency change with the inductor, and the external device measures temperature around the biosensor by measuring the resonance frequency change wirelessly. A bioelectronic patch device according to one embodiment of the present inventive concept comprises a drug patch comprising a polymer film comprising a biopolymer and a drug loaded in the polymer film, and a heater adjacent to the drug patch to heat the drug patch. A bioelectronic patch device according to another embodiment of the present inventive concept comprises a drug patch comprising a polymer film comprising a biopolymer and a drug loaded in the polymer film, a first protection layer disposed on the drug patch, a heater disposed on the first protection layer and heating the drug patch, a temperature sensor disposed on the first protection layer, spaced apart from the heater and measuring temperature of the heater, and a second protection layer covering the heater and the temperature sensor on the first protection layer.