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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10993433 B1

PDFFull Text
Date of Patent:
May. 04, 2021

Filed:

Oct. 14, 2016

Method of producing in vitro testicular constructs and uses thereof

Applicant:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

Samuel Pendergraft, Winston-Salem, NC (US);

Hooman Sadri-Ardekani, Lewisville, NC (US);

Anthony Atala, Winston-Salem, NC (US);

Colin Bishop, Clemmons, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorney:

Myers Bigel, P.A

Primary Examiner:

Robert J Yamasaki

Assistant Examiner:

Charles Zoltan Constantine

Int. Cl.
CPC ...
C12N 5/22 (2006.01); A01N 1/02 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A01N 1/021 (2013.01); A01N 1/0221 (2013.01); C12N 5/0697 (2013.01); C12N 2506/246 (2013.01); C12N 2510/04 (2013.01); C12N 2533/90 (2013.01); G01N 2500/10 (2013.01); G01N 2510/00 (2013.01); G01N 2520/00 (2013.01);
Abstract

A cell composition composed of spermatogonial stem cells, Sertoli cells, Leydig cells and optionally peritubular cells, is provided, as is a culture composition, artificial testicular construct, hydrogel composition, and device containing the same. A method for using the device as a physiologically relevant in vitro model of human testicular function to screen compounds for pharmacological or toxicological activity is also provided.

Find Patent Forward Citations

Pendergraft, Samuel. (2021). Method of producing in vitro testicular constructs and uses thereof (U.S. Patent No. 10993433). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10993433

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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