The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Aug. 29, 2016
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Gary Ruvkun, Newton, MA (US);
J. Amaranath Govindan, Boston, MA (US);
Assignee:
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); A61P 39/00 (2006.01); A61K 45/06 (2006.01); A61K 35/74 (2015.01); A61K 31/702 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/702 (2013.01); A61K 35/74 (2013.01); A61K 45/06 (2013.01); A61P 39/00 (2018.01); C12N 15/111 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01);
Abstract
Disclosed herein are compositions and methods for attenuating detoxification response and related symptoms thereof induced by translation defect. The compositions and methods herein are useful for attenuating detoxification response and/or treat related symptoms thereof in subjects comprising translation defect. The composition and methods herein are also useful for improving pharmacokinetics of a pharmaceutical compound.