The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Oct. 31, 2014
Applicant:
Resolve Therapeutics, Llc, Seattle, WA (US);
Inventors:
James Arthur Posada, May, ID (US);
Chris Gabel, Seattle, WA (US);
Assignee:
RESOLVE THERAPEUTICS, LLC, St. Petersburg, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); C12N 9/22 (2006.01); C07K 14/765 (2006.01); A61K 38/00 (2006.01); A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C07K 14/765 (2013.01); C12Y 301/21001 (2013.01); C12Y 301/27005 (2013.01); A61K 38/00 (2013.01); A61K 38/465 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01);
Abstract
The invention provides for hybrid nuclease-albumin molecules with increased pharmacokinetic properties. The hybrid nuclease-albumin molecules of the invention have one or more nuclease domains (e.g., an RNase and/or DNase domain) operably coupled to an albumin, or a variant or fragment thereof. The invention also provides methods of treating or preventing a condition associated with an abnormal immune response.