The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Jun. 20, 2017
Applicant:

Galderma S.a., Cham, CH;

Inventors:

Katarina Edsman, Alunda, SE;

Jean-Guy Boiteau, Valbonne, FR;

Assignee:

GALDERMA HOLDING SA, La Tour-de-Peilz, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08L 5/08 (2006.01); C08L 5/16 (2006.01); A61K 9/16 (2006.01); C08K 5/1515 (2006.01); A61K 8/02 (2006.01); A61Q 19/00 (2006.01); C08J 3/075 (2006.01); A61K 8/73 (2006.01); C08B 37/16 (2006.01); C08B 37/08 (2006.01); A61K 47/36 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); C08J 3/12 (2006.01); A61K 31/216 (2006.01);
U.S. Cl.
CPC ...
C08L 5/08 (2013.01); A61K 8/0283 (2013.01); A61K 8/735 (2013.01); A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 9/1694 (2013.01); A61K 47/36 (2013.01); A61Q 19/00 (2013.01); C08B 37/0012 (2013.01); C08B 37/0072 (2013.01); C08J 3/075 (2013.01); C08J 3/12 (2013.01); C08K 5/1515 (2013.01); C08L 5/16 (2013.01); A61K 31/216 (2013.01); C08J 2305/08 (2013.01); C08J 2305/16 (2013.01); C08J 2405/08 (2013.01); C08J 2405/16 (2013.01); C08L 2312/00 (2013.01);
Abstract

A hyaluronic acid product is comprising a cross-linked hyaluronic acid and one or more cyclodextrin molecules, and further comprising a guest molecule capable of forming a guest-host complex with the aminocyclodextrin molecule acting as a host, wherein the guest molecule is a retinoid, preferably adapalene, or a RAM BA. The hyaluronic acid is cross-linked by ether bonds, and the one or more cyclodextrin molecules are grafted onto the cross-linked hyaluronic acid by amide bonds, preferably using a triazine-based coupling reagent.


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