The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Feb. 09, 2016
Applicants:

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Sarah Cheal, New York, NY (US);

Hong Xu, New York, NY (US);

Steven Larson, New York, NY (US);

Nai-Kong Cheung, New York, NY (US);

Karl Dane Wittrup, Cambridge, MA (US);

Alice Tzeng, Beachwood, OH (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 39/00 (2006.01); A61K 51/10 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 51/0482 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01);
Abstract

Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.


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