The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Apr. 12, 2019
Applicant:

University of Kansas, Lawrence, KS (US);

Inventors:

Jane V. Aldrich, Lawrence, KS (US);

S P Sanjeewa Nilendra Senadheera, Lawrence, KS (US);

Assignee:

University of Kansas, Lawrence, KS (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/12 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/126 (2013.01); C07K 5/12 (2013.01); A61K 38/00 (2013.01);
Abstract

Cyclic tetrapeptide stereochemical isomers of CJ-15,208, pharmaceutical compositions from such cyclic tetrapeptides, and methods of using such pharmaceutical compositions. The cyclic tetrapeptide compounds and pharmaceutical compositions disclosed herein are potent analgesics active in several pain models with generally minimal tolerance and reduced likelihood to induce addiction relative to other known opiates.


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