The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
May. 16, 2017
Applicant:
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Yan Zhang, Richmond, VA (US);
Dana E. Selley, Richmond, VA (US);
William Dewey, Richmond, VA (US);
Hamid Abkarali, Richmond, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/30 (2006.01); C07D 489/08 (2006.01); A61P 25/04 (2006.01);
U.S. Cl.
CPC ...
C07D 489/08 (2013.01); A61P 25/04 (2018.01); A61P 25/30 (2018.01);
Abstract
Analogues of 6 α/β-naltrexamine (NAQ) are provided. The analogues are selective, reversible antagonists of the mu opioid receptor (MOR) that exhibit good blood brain barrier penetration. The compounds are used in the treatment of opioid addiction and other diseases and conditions, including for the treatment of pain.