The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Nov. 13, 2020
Applicant:

G1 Therapeutics, Inc., Research Triangle Park, NC (US);

Inventors:

Stephen Schneider, Research Triangle Park, NC (US);

Alexander Smith, Apex, NC (US);

Hannah S. White, Chapel Hill, NC (US);

Jay Copeland Strum, Hillsborough, NC (US);

Jaroslaw Mazurek, Amsterdam, NL;

Assignee:

G1 Therapeutics, Inc., Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/26 (2006.01); C07D 487/20 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/20 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 9/19 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); C07B 2200/13 (2013.01);
Abstract

An advantageous isolated morphic form of trilaciclib which is 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7′,8′-dihydro-6′H-spiro[cyclohexane-1,9′-pyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyrimidin]-6′-one, for example in the form of a di-hydrochloride salt or a dihydrochloride, dihydrate.


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