The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Jun. 03, 2019
Applicant:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Inventors:
Roland K. Strong, Seattle, WA (US);
Colin Correnti, Seattle, WA (US);
Leonidas Stamatatos, Seattle, WA (US);
Andrew McGuire, Seattle, WA (US);
Assignee:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/21 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61P 31/18 (2006.01); C07K 14/16 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); A61P 31/18 (2018.01); C07K 14/005 (2013.01); C07K 14/16 (2013.01); C12N 2740/16034 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01);
Abstract
Engineered and multimerized human immunodeficiency virus (HIV) envelope glycoproteins are described. The envelope glycoproteins can be multimerized using a heptamerization domain such as a C4b binding protein multimerization domain or a ferritin fusion. The engineered and multimerized envelope glycoproteins can derived from glycoprotein 120 (gp120) and can used as an HIV vaccine.