The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Dec. 09, 2016
Applicant:

Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd., New Delhi, IN;

Inventors:

Tarun Sharma, New Delhi, IN;

Neeraj Joshi, New Delhi, IN;

Vibhu Kanchan, New Delhi, IN;

Deepa Sikriwal, New Delhi, IN;

Nidhi Shukla, Ghaziabad, IN;

Davinder Gill, New Delhi, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/00 (2006.01); A61K 39/106 (2006.01); A01N 65/00 (2009.01); A01N 63/00 (2020.01); A61K 39/02 (2006.01); C07K 14/28 (2006.01); C12P 21/02 (2006.01); A61P 31/04 (2006.01); C12P 1/04 (2006.01); A61K 39/00 (2006.01); C12N 15/86 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
A61K 39/107 (2013.01); A61P 31/04 (2018.01); C07K 14/28 (2013.01); C12P 1/04 (2013.01); C12P 21/02 (2013.01); A61K 2039/521 (2013.01); C12N 1/20 (2013.01); C12N 15/86 (2013.01);
Abstract

The present invention relates to a novel process of production of purified recombinant cholera toxin B (rCTB) which provides protection against diarrhea caused by various bacteria such asand Enterotoxigenic(ETEC). More particularly, the present invention relates to a process of production of rCTB with significantly higher yield and higher purity. The present invention also relates to a vaccine formulation having synergistic protection againstand cross protection against ETEC.


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