The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2021

Filed:

Mar. 08, 2018
Applicants:

Hao Yan, Chandler, AZ (US);

Dawei Jiang, Madison, WI (US);

Zhilei GE, Tempe, AZ (US);

Hyung-jun Im, Seoul, KR;

Christopher England, Madison, WI (US);

Peng Huang, Guangdong, CN;

Chunhai Fan, Shanghai, CN;

Weibo Cai, Madison, WI (US);

Inventors:

Hao Yan, Chandler, AZ (US);

Dawei Jiang, Madison, WI (US);

Zhilei Ge, Tempe, AZ (US);

Hyung-jun Im, Seoul, KR;

Christopher England, Madison, WI (US);

Peng Huang, Guangdong, CN;

Chunhai Fan, Shanghai, CN;

Weibo Cai, Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/711 (2006.01); A61P 13/12 (2006.01); A61K 9/51 (2006.01); A61K 49/00 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01); A61K 9/00 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 31/711 (2013.01); A61K 9/51 (2013.01); A61K 49/0093 (2013.01); A61P 13/12 (2018.01); G01N 33/54346 (2013.01); G01N 33/587 (2013.01); A61K 9/0019 (2013.01); B82Y 5/00 (2013.01); C12N 2795/14121 (2013.01); C12N 2795/14142 (2013.01); G01N 2800/347 (2013.01);
Abstract

Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.


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