The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Dec. 24, 2013
Applicant:
Ramot AT Tel-aviv University, Ltd., Tel Aviv, IL;
Inventors:
Assignee:
RAMOT AT TEL-AVIV UNIVERSITY LTD., Tel Aviv, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7048 (2006.01); A61K 31/7052 (2006.01); A61P 25/28 (2006.01); A61P 25/00 (2006.01); A61P 25/14 (2006.01); G01N 33/53 (2006.01); G01N 33/567 (2006.01); A61K 49/00 (2006.01); A61P 21/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 31/7052 (2013.01); A61P 21/00 (2018.01); A61P 25/00 (2018.01); A61P 25/14 (2018.01); A61P 25/28 (2018.01); G01N 33/5008 (2013.01); G01N 2500/10 (2013.01);
Abstract
Disclosed is treatment of genetic neurodegenerative or neurodevelopmental diseases that are caused by or associated with nonsense mutations or premature termination codons using macrolides. Further disclosed are methods for identifying agents that induce read-through of nonsense mutations and premature termination codons and uses thereof.