The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Jun. 05, 2015
Applicant:
Flexus Biosciences, Inc., Princeton, NJ (US);
Inventors:
Juan Carlos Jaen, Burlingame, CA (US);
Maksim Osipov, Belmont, CA (US);
Jay Patrick Powers, Pacifica, CA (US);
Hunter Paul Shunatona, San Francisco, CA (US);
James Ross Walker, Menlo Park, CA (US);
Mikhail Zibinsky, Lodi, CA (US);
Assignee:
Flexus Biosciences, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/15 (2006.01); C07D 295/155 (2006.01); C07D 213/58 (2006.01); C07D 307/16 (2006.01); A61K 45/06 (2006.01); C07C 259/12 (2006.01); C07D 211/62 (2006.01); C07D 277/56 (2006.01); A61K 31/4409 (2006.01); A61K 31/167 (2006.01); A61K 31/196 (2006.01); A61K 31/24 (2006.01); A61K 31/27 (2006.01); A61K 31/341 (2006.01); A61K 31/40 (2006.01); A61K 31/426 (2006.01); A61K 31/4402 (2006.01); A61K 31/445 (2006.01); A61K 31/5375 (2006.01); C07C 259/14 (2006.01); C07C 271/28 (2006.01); C07D 207/09 (2006.01); C07D 211/34 (2006.01); C07D 277/30 (2006.01);
U.S. Cl.
CPC ...
A61K 31/15 (2013.01); A61K 31/167 (2013.01); A61K 31/196 (2013.01); A61K 31/24 (2013.01); A61K 31/27 (2013.01); A61K 31/341 (2013.01); A61K 31/40 (2013.01); A61K 31/426 (2013.01); A61K 31/4402 (2013.01); A61K 31/445 (2013.01); A61K 31/4409 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); C07C 259/12 (2013.01); C07C 259/14 (2013.01); C07C 271/28 (2013.01); C07D 207/09 (2013.01); C07D 211/34 (2013.01); C07D 211/62 (2013.01); C07D 213/58 (2013.01); C07D 277/30 (2013.01); C07D 277/56 (2013.01); C07D 295/155 (2013.01); C07D 307/16 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); Y02A 50/30 (2018.01);
Abstract
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.