The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 2021
Filed:
Dec. 15, 2016
Applicant:
Hovione Scientia Limited, Cork, IE;
Inventors:
Assignee:
Cipla Limited, Mumbai, IN;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/19 (2006.01); A61K 31/404 (2006.01); A61K 47/26 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 9/0075 (2013.01); A61K 9/1623 (2013.01); A61K 9/1682 (2013.01); A61K 9/19 (2013.01); A61K 31/404 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01);
Abstract
A method for the preparation of respirable zafirlukast monohydrate particles comprises the steps of preparation of an aqueous suspension of amorphous zafirlukast; size-reduction with conversion of the suspended zafirlukast into crystalline monohydrate nanoparticles; and isolation of the crystalline zafirlukast in the form of a dry powder. Also provided are zafirlukast respirable particles characterized by comprising crystalline monohydrate zafirlukast. Pharmaceutical compositions comprising the particles are also disclosed, as is the use of the particles or compositions for the treatment of respiratory diseases.