The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Jan. 16, 2018
Applicant:

Technion Research & Development Foundation Ltd., Haifa, IL;

Inventors:

Yonina Eldar, Haifa, IL;

Mordechai Segev, Haifa, IL;

Oren Solomon, Ashdod, IL;

Maor Mutzafi, Haifa, IL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G06T 3/40 (2006.01); G06T 5/10 (2006.01); G06T 5/50 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6458 (2013.01); G01N 21/6408 (2013.01); G06T 3/4053 (2013.01); G06T 5/10 (2013.01); G06T 5/50 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/30024 (2013.01);
Abstract

An imaging apparatus () includes an interface () and a processor (). The interface is configured to receive a sequence of images of an object () acquired at respective acquisition times, the object is labeled with fluorescent emitters. The images depict intensity fluctuations of emitters on an acquisition grid, and the intensity fluctuations being uncorrelated among the emitters and during an overall time over which the images in the sequence are acquired. The a processor is configured to calculate a temporal correlation function of the intensity fluctuations over the sequence of images, and to estimate locations of the emitters on a super-resolution grid having a higher resolution than the acquisition grid, by applying to the temporal correlation function a recovery process in which the locations on the super-resolution grid are assumed to be sparse or compressible in a predefined domain. The recovery process includes a sparse-recovery process or a regularized process.


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