The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Nov. 20, 2018
Capitalbio Technology Corporation, Beijing, CN;
Tsinghua University, Beijing, CN;
Yang Li, Beijing, CN;
Guanbin Zhang, Beijing, CN;
Di Jiang, Beijing, CN;
Guangxin Xiang, Beijing, CN;
Wanli Xing, Beijing, CN;
Jing Cheng, Beijing, CN;
CAPITALBIO TECHNOLOGY CORPORATION, Beijing, CN;
TSINGHUA UNIVERSITY, Beiting, CN;
Abstract
A method for labeling target molecules coupled to particles for the detection of the target molecules using a microarray chip, comprises: providing a functionalized microparticle, wherein the microparticle is coated with one or more functional group; providing a modification group on each of the target molecules to be detected to form modified target molecules; contacting the functionalized microparticle with the modified target molecules; coupling a luminophore to the complex between the functionalized microparticle and the modified target molecules, thereby directly or indirectly labeling each modified target molecules with the luminophore. By directly or indirectly labeling the target molecules with the luminophore, the method reduces the cost of fluorescence detection, and avoids PCR inhibition derived from traditional fluorescence labeling molecules.