The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Dec. 12, 2016
Applicant:
Mcmaster University, Hamilton, CA;
Inventors:
Assignee:
McMaster University, Hamilton, CA;
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/04 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/04 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); C12Q 2525/207 (2013.01); C12Q 2525/307 (2013.01); C12Q 2561/113 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/166 (2013.01); C12Q 2600/178 (2013.01);
Abstract
The present application is directed to biosensors and methods for detecting a microorganism target in a sample using a mechanically interlocked nucleic acid catanane, wherein an enzyme from the microorganism target or that is activated by a molecule from the microorganism target cleaves a linkage in a first single-stranded nucleic acid ring of the catanane structure, allowing rolling-circle amplification to occur and the presence of rolling-circle amplification products indicates the presence of the microorganism in the sample.