The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
May. 19, 2017
Applicant:
Teknologian Tutkimuskeskus Vtt Oy, Espoo, FI;
Inventors:
Assignee:
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY, Espoo, FI;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/58 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12P 7/42 (2006.01); C12P 7/44 (2006.01); C12R 1/685 (2006.01); C12R 1/69 (2006.01); C12R 1/885 (2006.01); C12Q 1/26 (2006.01);
U.S. Cl.
CPC ...
C12P 7/58 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12P 7/42 (2013.01); C12P 7/44 (2013.01); C12Q 1/26 (2013.01); C12R 1/685 (2013.01); C12R 1/69 (2013.01); C12R 1/885 (2013.01); C12Y 101/01021 (2013.01); C12Y 101/01035 (2013.01); C12Y 101/01203 (2013.01); C12Y 102/01031 (2013.01); C12Y 501/02002 (2013.01);
Abstract
The present invention relates to a field of genetically modified fungal cells and converting galacturonic acid to meso-galactaric acid, more precisely to a method of producing meso-galactaric acid. The invention further relates to recombinant fungal cells having a specific combination of modifications including but not limited to expression of uronate dehydrogenase enzyme, reduced D-galacturonic acid reductase activity, and furthermore reduced meso-galactaric acid catabolism, as well as uses and methods related thereto.