The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Mar. 29, 2016
Applicant:

Catalyst Biosciences, Inc., South San Francisco, CA (US);

Inventors:

Edwin L. Madison, San Francisco, CA (US);

Christopher Thanos, Tiburon, CA (US);

Grant Ellsworth Blouse, Copenhagen S, DK;

Assignee:

Catalyst Biosciences, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); A61K 38/48 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/644 (2013.01); A61K 38/4846 (2013.01); C12Y 304/21022 (2013.01); A61K 48/00 (2013.01);
Abstract

Nucleic acid molecules encoding modified factor IX (FIX) polypeptides and uses thereof are provided. Such modified FIX polypeptides include FIXa and other forms of FIX. Among the modified FIX polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.


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