The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Feb. 04, 2020
Applicant:

Galderma Holding SA, La Tour-de-Peilz, CH;

Inventors:

Morgan Karlsson, Knivsta, SE;

Anne Helander Kenne, Marsta, SE;

Åke Öhrlund, Uppsala, SE;

Assignee:

GALDERMA HOLDING SA, La Tour-de-Peilz, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); A61K 8/04 (2006.01); A61K 8/73 (2006.01); A61K 31/728 (2006.01); A61Q 19/00 (2006.01); D01F 9/00 (2006.01); A61Q 19/08 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 8/042 (2013.01); A61K 8/735 (2013.01); A61K 9/0024 (2013.01); A61K 31/728 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); D01F 9/00 (2013.01); A61K 2800/91 (2013.01);
Abstract

A method for manufacturing a shaped cross-linked hyaluronic acid product including the step of subjecting a non-cross-linked precipitated hyaluronic acid substrate in a desired shape to a single cross-linking reaction in a liquid medium having a pH of 11.5 or higher and including one or more polyfunctional cross-linking agent(s) and an amount of one or more organic solvent(s) giving precipitating conditions for hyaluronic acid, under suitable conditions to obtain a precipitated, shaped cross-linked hyaluronic acid product having a degree of modification of 1-40 cross-linking agent units per 1000 disaccharide units.


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