The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Mar. 11, 2014
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Cristhian J. Ildefonso, Gainesville, FL (US);

Alfred S. Lewin, Gainesville, FL (US);

Qiuhong Li, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 48/00 (2006.01); A61K 9/00 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 9/0048 (2013.01); A61K 48/005 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/10 (2013.01); C12N 15/86 (2013.01); C12N 2740/15041 (2013.01); C12N 2750/14141 (2013.01);
Abstract

The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or ocular inflammation. In an exemplary embodiment, a method is disclosed that involves administering an expression vector that delivers a secretable and cell penetrating CARD to a subject in need of treatment or prevention of age-related macular degeneration or another condition involving macular degeneration or ocular neovascularization.


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