The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Oct. 02, 2019
Applicant:

Allergan Sales, Llc, Madison, NJ (US);

Inventors:

Robert M. Moriarty, Michiana Shores, IN (US);

Achampeta Rathan Prasad, Hyderabad, IN;

John Gregory Reid, Groton, MA (US);

Roy A. Swaringen, Jr., Durham, NC (US);

Assignee:

Allergan Sales, LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 9/00 (2006.01); A61K 31/575 (2006.01); C07J 1/00 (2006.01); C07J 5/00 (2006.01); C07J 13/00 (2006.01); C07J 41/00 (2006.01);
U.S. Cl.
CPC ...
C07J 9/005 (2013.01); A61K 31/575 (2013.01); C07J 1/0011 (2013.01); C07J 5/0053 (2013.01); C07J 9/00 (2013.01); C07J 13/007 (2013.01); C07J 41/0061 (2013.01); Y02P 20/55 (2015.11);
Abstract

Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.


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