The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Nov. 02, 2018
Applicant:
Aclaris Therapeutics, Inc., Wayne, PA (US);
Inventors:
David Randolph Anderson, Salem, CT (US);
Susan Landis Hockerman, Kirkwood, MO (US);
James Robert Blinn, O'Fallon, MO (US);
Eric Jon Jacobsen, Chesterfield, MO (US);
Assignee:
ACLARIS THERAPEUTICS, INC., Wayne, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4545 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/4545 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.