The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Mar. 11, 2016
Applicants:
Carthera, Paris, FR;
Assistance Publique Hopitaux DE Paris, Paris, FR;
Universite Pierre ET Marie Curie (Paris 6), Paris, FR;
Inventors:
Assignees:
Carthera, Paris, FR;
Assistance Publique Hopitaux de Paris, Paris, FR;
Universite Pierre et Marie Curie (Paris 6), Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 7/00 (2006.01); A61K 41/00 (2020.01); A61K 31/555 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61K 31/495 (2013.01); A61K 31/555 (2013.01); A61K 41/0028 (2013.01); A61N 2007/0021 (2013.01);
Abstract
The present invention relates to a method for transiently disrupting a region of the blood-brain barrier (BBB) of a human using ultrasounds in the presence of an ultrasound contrast agent, and uses thereof. The method comprises the application of at least one ultrasound (US) beam with a pressure level higher than 1 MPa and a resonance frequency ranging from 0.5 to 1.5 MHz.