The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Feb. 23, 2018
Applicant:

Eth Zurich, Zurich, CH;

Inventors:

Marcy Zenobi-Wong, Zurich, CH;

Gemma Palazzolo, Zurich, CH;

Rami Mhanna, Zurich, CH;

Jana Becher, Jena, DE;

Stefanie Moller, Jena, DE;

Matthias Schnabelrauch, Jena, DE;

Assignee:

ETH ZURICH, Zurich, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/36 (2006.01); C12N 5/00 (2006.01); A01N 1/02 (2006.01); A61L 27/20 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61K 35/28 (2015.01); A61K 35/30 (2015.01); A61K 35/32 (2015.01); A61K 35/33 (2015.01); A61K 35/407 (2015.01); A61K 35/545 (2015.01);
U.S. Cl.
CPC ...
A61K 47/36 (2013.01); A01N 1/0231 (2013.01); A61K 35/28 (2013.01); A61K 35/30 (2013.01); A61K 35/32 (2013.01); A61K 35/33 (2013.01); A61K 35/407 (2013.01); A61K 35/545 (2013.01); A61L 27/20 (2013.01); A61L 27/383 (2013.01); A61L 27/3804 (2013.01); A61L 27/52 (2013.01); C12N 5/0012 (2013.01); A61L 2430/06 (2013.01); A61L 2430/32 (2013.01); C12N 2533/74 (2013.01);
Abstract

The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.


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