The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Jan. 10, 2018
Applicant:
Celltrion Inc., Incheon, KR;
Inventors:
Joon Won Lee, Incheon, KR;
Yeon Kyeong Shin, Incheon, KR;
Hye Young Kang, Incheon, KR;
Kwang Woo Kim, Incheon, KR;
So Young Kim, Incheon, KR;
Su Jung Kim, Incheon, KR;
Jun Seok Oh, Incheon, KR;
Won Yong Han, Incheon, KR;
Assignee:
CELLTRION INC., Incheon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/395 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 9/08 (2006.01); C07K 14/525 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61K 9/08 (2013.01); A61K 39/3955 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); C07K 14/525 (2013.01); C07K 16/241 (2013.01);
Abstract
Disclosed is a stable liquid formulation, comprising an antibody or antigen-binding portion thereof, an acetate buffer, glycine, and a surfactant, wherein the stable liquid formulation does not comprise at least one of sugar, a sugar alcohol and a metal salt, and the stable liquid formulation is still stable even upon high antibody content, and is superior in osmolality and viscosity, and subcutaneous administration thereof is possible.