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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10980859 B1

PDFFull Text
Date of Patent:
Apr. 20, 2021

Filed:

Mar. 02, 2016

In vivo individualized systemic immunotherapeutic method and device

Applicant:

Hangzhou Converd Co., Ltd., Zhejiang, CN;

Inventors:

Fang Hu, Zhejiang, CN;

Ronghua Zhao, Zhejiang, CN;

Siyi Chen, Zhejiang, CN;

Bo Wu, Zhejiang, CN;

Huiqun Xia, Zhejiang, CN;

Yanjun Zheng, Zhejiang, CN;

Assignee:

Hangzhou Converd Co., Ltd., Zhejiang, CN;

Attorney:

The Webb Law Firm

Primary Examiner:

Karen A Canella

Int. Cl.
CPC ...
A61K 38/19 (2006.01); A61K 35/761 (2015.01); A61K 45/06 (2006.01); A61K 31/513 (2006.01); A61K 31/7068 (2006.01); A61K 31/704 (2006.01); A61K 33/24 (2019.01); A61K 31/475 (2006.01); A61K 35/768 (2015.01); A61K 38/48 (2006.01); A61K 35/763 (2015.01); A61K 35/74 (2015.01); A61K 38/55 (2006.01); A61K 35/766 (2015.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/193 (2013.01); A61K 31/475 (2013.01); A61K 31/513 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 35/74 (2013.01); A61K 35/761 (2013.01); A61K 35/763 (2013.01); A61K 35/766 (2013.01); A61K 35/768 (2013.01); A61K 38/191 (2013.01); A61K 38/4873 (2013.01); A61K 38/55 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07K 16/30 (2013.01); C12N 7/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/76 (2013.01); C12N 2710/10332 (2013.01); Y02A 50/30 (2018.01);
Abstract

The invention provides an in vivo individualized systemic immunotherapeutic method and device. The method includes, in a non-sequential manner: (1) increasing release amount of tumor antigens at a tumor site; (2) at the tumor site, increasing level of proteins capable of adhering to and/or wrapping the tumor antigens; (3) at the tumor site, increasing level of dedicated antigen-presenting cells involved in immunity, and establishing, between the dedicated antigen-presenting cells and immune effector cells, a close connection capable of activating the immune effector cells; and (4) at the tumor site, increasing level and improving function of the immune effector cells. The steps (1)-(4) each reaches a maximum value at a respective time which overlaps with each other maximally, as well as at a respective site which overlaps with each other maximally. The invention combines oncolytic therapy and immunotherapy, in individualized systemic immunotherapy, and provides significantly improved therapeutic effect.

Find Patent Forward Citations

Hu, Fang. (2021). In vivo individualized systemic immunotherapeutic method and device (U.S. Patent No. 10980859). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10980859

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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