The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Dec. 01, 2017
Applicant:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Inventors:
Kun Ping Lu, Newton, MA (US);
Xiao Zhen Zhou, Newton, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/36 (2006.01); A61P 35/00 (2006.01); A61P 19/02 (2006.01); A61K 31/203 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 33/36 (2013.01); A61K 9/0002 (2013.01); A61K 31/203 (2013.01); A61P 19/02 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to the treatment of Pin1-associated disorders (e.g., disorders characterized by elevated Pin1 activity) with arsenic trioxide, optionally in combination with a retinoic acid compound. Pin1-associated disorders may include, for example, proliferative disorders (e.g., cancers), inflammatory conditions, and autoimmune disorders associated with aberrant levels of Pin1 activity.