The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Apr. 24, 2018
Ucb Biopharma Srl, Brussels, BE;
Sanofi, Paris, FR;
Daniel Christopher Brookings, Slough, GB;
Teresa De Haro Garcia, Slough, GB;
Yann Foricher, Paris, FR;
Helen Tracey Horsley, Slough, GB;
Martin Clive Hutchings, Slough, GB;
James Andrew Johnson, Slough, GB;
Malcolm Maccoss, Seabrook Island, SC (US);
Mengyang Xuan, Slough, GB;
Zhaoning Zhu, Slough, GB;
UCB Biopharma SRL, Brussels, BE;
Sanofi, Paris, FR;
Abstract
Disclosed herein are compounds of formula (I) and pharmaceutically acceptable salt thereof, wherein variables X, R, R, and Rare defined herein. These compounds are potent modulators of human TNFα activity and, accordingly, of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.