The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2021
Filed:
Feb. 11, 2018
Beijing Scitech-mq Pharmaceuticals Limited, Beijing, CN;
Qiang Zhang, Beijing, CN;
Hongbo Zhang, Beijing, CN;
Leifu Yang, Beijing, CN;
Hailong Yang, Beijing, CN;
Likai Zhou, Beijing, CN;
Nanqiao Zheng, Beijing, CN;
Shannan Yu, Beijing, CN;
Zhongxiang Wang, Beijing, CN;
Shouye Feng, Beijing, CN;
Zhanqiang Xu, Beijing, CN;
BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED, Beijing, CN;
Abstract
The present invention relates to a urea-substituted aromatic ring-linked dioxinoquinazoline and a urea-substituted aromatic ring-linked dioxinoquinoline of Formula (I), or a pharmaceutically acceptable salt thereof or a hydrate thereof. Also provided are the preparation of the compound as shown in Formula (I) and the pharmaceutically acceptable salt thereof and the use thereof as a drug. The drug is used as an inhibitor of tyrosine kinases (e.g., VEGFR-2, C-RAF, B-RAF) for treating tyrosine kinase-related diseases.