The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2021

Filed:

Jun. 07, 2019
Applicant:

Biocytogen Pharmaceuticals (Beijing) Co., Ltd., Beijing, CN;

Inventors:

Yuelei Shen, Beijing, CN;

Yang Bai, Beijing, CN;

Rui Huang, Beijing, CN;

Chengzhang Shang, Beijing, CN;

Yanan Guo, Beijing, CN;

Meiling Zhang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C07H 21/04 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C07K 16/2878 (2013.01); G01N 33/5011 (2013.01); A01K 2207/15 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01);
Abstract

The present disclosure relates to genetically modified non-human animals (e.g., genetically-modified mice) that express a human or chimeric (e.g., humanized) CD27. The present disclosure also relates to methods of generating the genetically-modified animals (e.g., genetically modified mice), and methods of using the genetically modified non-human animals (e.g., genetically modified mice) described herein.


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