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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10976323 B1

PDFFull Text
Date of Patent:
Apr. 13, 2021

Filed:

Feb. 09, 2018

Methods for measuring concentrations of biomolecules in biofluids

Applicant:

C2n Diagnostics Llc, Saint Louis, MS (US);

Inventors:

Kristopher Michael Kirmess, St. Louis, MO (US);

Kevin Edward Yarasheski, St. Louis, MO (US);

Matthew R. Meyer, Chesterfield, MO (US);

Assignee:

C2N Diagnostics LLC, Saint Louis, MO (US);

Attorney:

DLA Piper LLP (US)

Primary Examiner:

Benjamin R Whatley

Assistant Examiner:

Jean Caraballo-Lean

Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/60 (2006.01); C12N 9/76 (2006.01); G01N 33/48 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); C12N 9/6427 (2013.01); C12Q 1/00 (2013.01); G01N 33/48 (2013.01); G01N 33/60 (2013.01); G01N 33/6896 (2013.01); G01N 2333/4709 (2013.01); G01N 2458/15 (2013.01); G01N 2560/00 (2013.01); G01N 2800/2821 (2013.01);
Abstract

The present invention provides methods for measuring the absolute concentration of Tau, and other protein, peptide fragments and proteoforms in CSF and plasma samples collected from a subject. Such biomolecules may be implicated in one or more neurological and neurodegenerative diseases or disorders. Also provided is a method for determining whether a therapeutic agent affects the CSF or plasma concentration of a central nervous system derived biomolecule. Also provided are kits for performing the methods of the invention.

Find Patent Forward Citations

Kirmess, Kristopher. (2021). Methods for measuring concentrations of biomolecules in biofluids (U.S. Patent No. 10976323). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10976323

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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