The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Jan. 23, 2017
Applicant:

Electrophoretics Limited, Surrey, GB;

Inventors:

Peter Schulz-Knappe, Frankfurt-am-Main, DE;

Ian Pike, Surrey, GB;

Karsten Kuhn, Hofheim Am Taunus, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 1/28 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01); H01J 49/00 (2006.01); G01N 33/96 (2006.01);
U.S. Cl.
CPC ...
G01N 33/58 (2013.01); G01N 1/28 (2013.01); G01N 33/6848 (2013.01); G01N 33/6851 (2013.01); G01N 33/96 (2013.01); H01J 49/0009 (2013.01); G01N 2001/2893 (2013.01); G01N 2333/4703 (2013.01); G01N 2333/765 (2013.01); G01N 2333/775 (2013.01); G01N 2458/15 (2013.01); G01N 2560/00 (2013.01); G01N 2570/00 (2013.01); Y10T 436/105831 (2015.01);
Abstract

Provided is a method of assaying for an analyte, including combining a test sample having the analyte, with a calibration sample having at least two different aliquots of the analyte, each aliquot having a different known quantity of the analyte. The test sample and each aliquot are differentially labeled with one or more isobaric mass labels each with a mass spectrometrically distinct mass marker group, such that the test sample and each aliquot of the calibration sample can be distinguished by mass spectrometry. The method further includes determining by mass spectrometry the quantity of analyte in the test sample and in each aliquot, and calibrating the quantity of analyte in the test sample against known and determined quantities of analytes in the aliquots.


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