The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Sep. 09, 2015
Applicants:

Takara Bio Inc., Shiga, JP;

Kyushu University, National University Corporation, Fukuoka, JP;

Educational Corporation Kansai Bunri Sougougakuen, Shiga, JP;

Inventors:

Takashi Uemori, Otsu, JP;

Yoshizumi Ishino, Fukuoka, JP;

Takehiro Sagara, Minamishimabara, JP;

Sonoko Ishino, Fukuoka, JP;

Takeshi Yamagami, Fukuoka, JP;

Tsuyoshi Shirai, Nagahama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12N 9/22 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/68 (2013.01); C12N 9/22 (2013.01); C12N 15/09 (2013.01);
Abstract

A polypeptide having a mismatch endonuclease activity of recognizing a mismatch and cleaving the mismatch; a mismatch-specific cleavage reaction using the polypeptide; a method for removing an error in a nucleic acid amplification reaction utilizing the polypeptide; a method for inhibiting the amplification of a nucleic acid comprising a specific nucleotide sequence during a nucleic acid amplification reaction; and a method for detecting a nucleic acid having a single-nucleotide polymorphism mutation utilizing the inhibition method.


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