The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Apr. 22, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Matthias Hebrok, Belmont, CA (US);
Holger Andreas Russ, San Francisco, CA (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C07K 14/62 (2006.01); C07K 14/50 (2006.01); C07K 14/485 (2006.01); C07K 14/495 (2006.01); A61P 3/10 (2006.01); A61K 35/39 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0678 (2013.01); A61K 35/39 (2013.01); A61P 3/10 (2018.01); C07K 14/485 (2013.01); C07K 14/495 (2013.01); C07K 14/50 (2013.01); C07K 14/62 (2013.01); C12N 5/0677 (2013.01); C12N 2501/11 (2013.01); C12N 2501/117 (2013.01); C12N 2501/15 (2013.01); C12N 2501/155 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2506/02 (2013.01);
Abstract
Methods are provided for the simple, fast, effective and safe directed differentiation of embryonic stem cells into pancreatic beta-like cells secreting insulin in response to glucose levels. The cells are useful transplant therapeutics for diabetic individuals.