The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Nov. 07, 2019
Applicants:
Orgenesis Ltd., Tel Aviv, IL;
Tel Hashomer Medical Research Infrastructure and Services Ltd., Ramat Gan, IL;
Inventor:
Sarah Ferber, Tel Aviv, IL;
Assignees:
ORGENESIS LTD., Tel Aviv, IL;
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD., Ramat Gan, IL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0676 (2013.01); G01N 33/54306 (2013.01); C12N 2501/11 (2013.01); C12N 2501/395 (2013.01); C12N 2501/415 (2013.01); C12N 2501/998 (2013.01); C12N 2501/999 (2013.01); C12N 2506/22 (2013.01);
Abstract
Disclosed herein are methods for manufacturing transdifferentiated populations of non-pancreatic human insulin producing cells, and methods for enriching populations of non-pancreatic β-cells for cells comprising an enriched capacity for transcription factor-induced transdifferentiation into a pancreatic β-cell phenotype and function.