The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

May. 24, 2018
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Lorenzo Berti, San Diego, CA (US);

Andrew A. Brown, Nr Saffron Walden, GB;

Wayne N. George, Nr Saffron Walden, GB;

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 7/12 (2006.01); C12Q 1/6876 (2018.01); C08F 8/00 (2006.01); C12Q 1/6874 (2018.01); B01J 19/00 (2006.01); C09D 133/26 (2006.01); C12Q 1/6837 (2018.01); C08F 220/60 (2006.01);
U.S. Cl.
CPC ...
C08J 7/12 (2013.01); B01J 19/0046 (2013.01); C08F 8/00 (2013.01); C09D 133/26 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/6876 (2013.01); B01J 2219/00529 (2013.01); B01J 2219/00533 (2013.01); B01J 2219/00619 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/00637 (2013.01); B01J 2219/00722 (2013.01); C08F 220/603 (2020.02); C08J 2335/00 (2013.01);
Abstract

The present application relates to a method for preparing a functionalized surface and the use in DNA sequencing and other diagnostic applications. A substrate with a surface comprising a silane or a silane derivative covalently attached to optionally substituted cycloalkene or optionally substituted heterocycloalkene can be used for direct conjugation with a functionalized molecule of interest, such as a polymer, a hydrogel, an amino acid, a nucleoside, a nucleotide, a peptide, a polynucleotide, or a protein. In some embodiments, the silane or silane derivative contains optionally substituted norbornene or norbornene derivatives.


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