The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Sep. 01, 2016
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Widusha Illeperuma, Cambridge, MA (US);

Zhigang Suo, Lexington, MA (US);

Joost J. Vlassak, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 3/075 (2006.01); C08J 3/24 (2006.01); G01L 1/14 (2006.01); C08F 220/06 (2006.01); C08F 20/56 (2006.01); C08K 3/30 (2006.01); C08K 3/26 (2006.01); C08K 3/10 (2018.01); C08K 3/22 (2006.01); C08K 3/16 (2006.01);
U.S. Cl.
CPC ...
C08J 3/075 (2013.01); C08F 20/56 (2013.01); C08F 220/06 (2013.01); C08J 3/24 (2013.01); C08K 3/10 (2013.01); C08K 3/16 (2013.01); C08K 3/22 (2013.01); C08K 3/26 (2013.01); C08K 3/30 (2013.01); G01L 1/142 (2013.01); C08J 2305/04 (2013.01); C08J 2333/26 (2013.01); C08K 2003/162 (2013.01); C08K 2003/164 (2013.01); C08K 2003/166 (2013.01); C08K 2003/168 (2013.01); C08K 2003/2206 (2013.01); C08K 2003/2217 (2013.01); C08K 2003/262 (2013.01); C08K 2003/265 (2013.01); C08K 2003/3045 (2013.01); C08K 2003/3063 (2013.01);
Abstract

Hydrogel compositions, and corresponding methods of making, are provided. The hydrogels do not freeze, or only partially freeze, over a wide range of temperatures below the freezing temperature of water. Concurrently, these hydrogels also retain their room temperature mechanical properties (e.g., strength, modulus, elasticity) over a wide range of temperatures, including temperatures below the freezing temperature of water. The hydrogels are synthesized by adding a suitable amount of a salt together with previously cross-linked polymer gel. Hydration of the gel with aqueous solutions containing the prescribed salts not only depresses the hydrogel freezing point but protects the structure. For example, the salts do not allow the hydrogel to completely freeze, thus protecting the hydrogel from brittle failure. Whether the hydrogels partially freeze or remain non-frozen when chilled below the freezing temperature of water is determined by concentration of salt within the hydrogel.


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