The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
May. 12, 2017
Applicant:
Medimmune, Llc, Gaithersburg, MD (US);
Inventors:
Manuel Baca, Gaithersburg, MD (US);
Stacey Drabic, Gaithersburg, MD (US);
Peter Emtage, San Francisco, CA (US);
Ronald Herbst, Gaithersburg, MD (US);
Assignee:
MEDIMMUNE, LLC, Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/705 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01); C12N 15/62 (2006.01); A61K 38/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C07K 14/70575 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); C12N 15/62 (2013.01); A61K 38/00 (2013.01); C07K 2317/30 (2013.01); C07K 2319/30 (2013.01); C12P 21/00 (2013.01);
Abstract
Provided herein is a CD40L-Fc fusion protein and methods of using the fusion protein in the treatment of cancer comprising administering the CD40L-Fc fusion protein or the CD40L-Fc fusion protein in combination with one or more immune checkpoint inhibitors (e.g., an anti-CTLA4 antibody, anti-PD-L1 antibody).