The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Aug. 09, 2019
Applicant:
Roche Glycart Ag, Schlieren, CH;
Inventors:
Thomas Hofer, Zurich, CH;
Changhua Ji, Livingston, NJ (US);
Ekkehard Moessner, Kreuzlingen, CH;
Pablo Umana, Wollerau, CH;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/56 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); C07K 14/56 (2013.01); A61K 2039/505 (2013.01); C07K 2317/33 (2013.01); C07K 2317/52 (2013.01); C07K 2317/526 (2013.01); C07K 2317/56 (2013.01); C07K 2317/71 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01);
Abstract
The present invention generally relates to antibodies specific for asialoglycoprotein receptor (ASGPR) and their use for selectively delivering effector moieties that influence cellular activity. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies of the invention, and to methods of using them in the treatment of disease.