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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10975149 B1

PDFFull Text
Date of Patent:
Apr. 13, 2021

Filed:

Dec. 16, 2016

Inhibition of cytokine-induced sh2 protein in nk cells

Applicant:

The Walter and Eliza Hall Institute of Medical Research, Parkville, AU;

Inventors:

Nicholas D. Huntington, Parkville, AU;

Sandra E. Nicholson, Parkville, AU;

Jeff Babon, Parkville, AU;

Tatiana Kolesnik, Parkville, AU;

Assignee:

The Walter and Eliza Hall Institute of Medical Research;

Attorney:

Fox Rothschild LLP

Primary Examiner:

Daniel C Gamett

Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 16/28 (2006.01); A61K 38/17 (2006.01); C07K 16/22 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); A61K 31/713 (2006.01); A61K 39/395 (2006.01); A61K 35/17 (2015.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 31/506 (2013.01); A61K 31/713 (2013.01); A61K 35/17 (2013.01); A61K 38/04 (2013.01); A61K 38/1709 (2013.01); A61K 39/395 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 16/18 (2013.01); C07K 16/22 (2013.01); C07K 16/2803 (2013.01); G01N 33/566 (2013.01); G01N 33/6863 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01);
Abstract

The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.

Find Patent Forward Citations

Huntington, Nicholas. (2021). Inhibition of cytokine-induced sh2 protein in nk cells (U.S. Patent No. 10975149). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10975149

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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