The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Apr. 26, 2018
Applicants:
Aduro Biotech, Inc., Berkeley, CA (US);
Novartis Ag, Basel, CH;
Inventors:
Justin Leong, Union City, CA (US);
Chudi Obioma Ndubaku, Oakland, CA (US);
Jeffrey McKenna, Carlisle, MA (US);
Assignees:
CHINOOK THERAPEUTICS, INC., Seattle, WA (US);
NOVARTIS AG, Basel, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 21/04 (2006.01); A61P 35/04 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61P 35/04 (2018.01); A61K 45/06 (2013.01); A61K 2039/585 (2013.01);
Abstract
The present invention provides the cyclic dinucleotide compound 2'2′-RR-(3′F-A)(3′F-A) as a highly active immune stimulator that activates DCs via the cytoplasmic receptor known as STING (Stimulator of Interferon Genes), and compositions and uses thereof.