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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10975085 B1

PDFFull Text
Date of Patent:
Apr. 13, 2021

Filed:

Jun. 10, 2019

Process for preparing a composition comprising an enantiomeric excess of greater than or equal to 90% of the (r)-enantiomer of a compound of formula iii

Applicants:

Incyte Holdings Corporation, Wilmington, DE (US);

Incyte Corporation, Wilmington, DE (US);

Inventors:

Jiacheng Zhou, Newark, DE (US);

James D. Rodgers, Landenberg, PA (US);

Haisheng Wang, Hockessin, DE (US);

Assignees:

Incyte Holdings Corporation, Wilmington, DE (US);

Incyte Corporation, Wilmington, DE (US);

Attorneys:

Brian C. Trinque

Lathrop GPM LLP

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07F 7/18 (2006.01); C07F 7/10 (2006.01); C07F 5/02 (2006.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07F 5/025 (2013.01); C07F 7/083 (2013.01); C07F 7/10 (2013.01); C07F 7/1892 (2013.01); Y02P 20/55 (2015.11);
Abstract

The present invention is related to processes for preparing a composition comprising (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile, and related synthetic intermediate compounds. This compound is useful as an inhibitor of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.

Find Patent Forward Citations

Zhou, Jiacheng. (2021). Process for preparing a composition comprising an enantiomeric excess of greater than or equal to 90% of the (r)-enantiomer of a compound of formula iii (U.S. Patent No. 10975085). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10975085

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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