The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Jan. 20, 2017
Applicant:

Sandoz Ag, Basel, CH;

Inventor:

Hannes Lengauer, Kundl, AT;

Assignee:

Sandoz AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/06 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 207/06 (2013.01); A61K 9/20 (2013.01); A61K 9/48 (2013.01); A61K 9/0053 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to crystalline eravacycline bis-hydrochloride and to a process for its preparation. Furthermore, the invention relates to the use of crystalline eravacycline bis-hydrochloride for the preparation of pharmaceutical compositions. The invention further relates to pharmaceutical compositions comprising an effective amount of crystalline eravacycline bis-hydrochloride. The pharmaceutical compositions of the present invention can be used as medicaments, in particular for treatment and/or prevention of bacterial infections e.g. caused by Gram negative pathogens or Gram positive pathogens, in particular caused by multidrug resistant Gram negative pathogens. The pharmaceutical compositions of the present invention can thus be used as medicaments for e.g. the treatment of complicated intra-abdominal and urinary tract infection.


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