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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10974166 B1

PDFFull Text
Date of Patent:
Apr. 13, 2021

Filed:

Aug. 04, 2017

Protein having affinity for immunoglobulin, affinity separation agent and column for liquid chromatography using the same

Applicant:

Mitsubishi Chemical Corporation, Tokyo, JP;

Inventors:

Shoya Yoda, Kanagawa, JP;

Satoru Misawa, Kanagawa, JP;

Risa Nakata, Kanagawa, JP;

Assignee:

Mitsubishi Chemical Corporation, Tokyo, JP;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Daniel E Kolker

Assistant Examiner:

James L Rogers

Int. Cl.
CPC ...
B01D 15/08 (2006.01); B01D 15/38 (2006.01); C12N 15/00 (2006.01); C07K 1/22 (2006.01); C07K 17/12 (2006.01); C07K 14/31 (2006.01); C12N 15/09 (2006.01); B01J 20/24 (2006.01); B01J 20/289 (2006.01); B01J 20/32 (2006.01); G01N 30/02 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
B01D 15/08 (2013.01); B01D 15/3809 (2013.01); B01J 20/24 (2013.01); B01J 20/289 (2013.01); B01J 20/321 (2013.01); B01J 20/3204 (2013.01); B01J 20/3212 (2013.01); B01J 20/3219 (2013.01); B01J 20/3274 (2013.01); C07K 1/22 (2013.01); C07K 14/31 (2013.01); C07K 17/12 (2013.01); C12N 15/09 (2013.01); G01N 30/02 (2013.01); C07K 1/00 (2013.01); C12N 15/00 (2013.01);
Abstract

One embodiment of the present invention is a protein having affinity for an immunoglobulin, which is a protein having two or more domains derived from any of the amino acid sequences of E, D, and A domains of protein A, and in the amino acid sequence of at least one of the domains, one or more lysines are included, and the C-terminal lysine is deleted or substituted, or a protein having affinity for an immunoglobulin, which is a protein having two or more domains derived from any of B, C, and Z domains of protein A, and in the amino acid sequence of at least one of the domains, one or more lysines are included, and lysine at position 4 and the C-terminal lysine are deleted or substituted.

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