The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Mar. 14, 2014
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Karl Deisseroth, Stanford, CA (US);
Sung-Yon Kim, Cambridge, MA (US);
Avishek Adhikari, Palo Alto, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61N 5/06 (2006.01); A61K 48/00 (2006.01); C12N 15/86 (2006.01); A61K 31/00 (2006.01); A61K 45/00 (2006.01); A61N 1/36 (2006.01);
U.S. Cl.
CPC ...
A61N 5/0618 (2013.01); A61K 31/00 (2013.01); A61K 41/00 (2013.01); A61K 45/00 (2013.01); A61N 5/0622 (2013.01); A61N 1/36121 (2013.01); A61N 5/062 (2013.01); A61N 2005/0612 (2013.01); A61N 2005/0663 (2013.01);
Abstract
The present disclosure provides methods of modulating a feature of a behavioral state. The methods involve inhibiting or activating the activity of a bed nucleus of stria terminalis (BNST) neuron, a BNST subnucleus, or a neuronal output to or from a BNST neuron. Animals encounter environmental conditions that require rapid switching among different behavioral states to increase the likelihood of survival and reproduction.