The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Jun. 20, 2016
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Hans-Georg Lerchen, Leverkusen, DE;
Yolanda Cancho Grande, Leverkusen, DE;
Beatrix Stelte-Ludwig, Wülfrath, DE;
Anette Sommer, Berlin, DE;
Christoph Mahlert, Wuppertal, DE;
Anne-Sophie Rebstock, Champagne au Mont d'Or, FR;
Simone Greven, Dormagen, DE;
Nils Griebenow, Dormagen, DE;
Jan Tebbe, Cologne, DE;
Oliver Kensch, Pulheim, DE;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Abstract
The invention relates to site specific homogeneous binder drug conjugates of kinesin spindle protein inhibitors, to active metabolites of these conjugates, to processes for preparing these conjugates, to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.